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3.5 Peroxisomes: lipid metabolism and ROS detoxification in axis balance Peroxisomes are involved in lipid metabolism (e.g., PUFA -oxidation) and ROS detoxification (e.g., hydrogen peroxide [H 2 O 2 ] catabolism)functions that directly modulate the ferroptosis-immune-metabolic axis (94)

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Both the EPAC2 and PKA are activated in response to elevated cAMP [54]

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